Fantasies about stem cell therapy in chronic ischemic stroke patients.
作者： Young Seo Kim , Dan-il Chung , Hojin Choi , Wonki Baek , Hyun Young Kim
关键词: Clinical evidence 、 Young adult 、 Biology 、 Chronic disease 、 Stem-cell therapy 、 Internal medicine 、 Ischemic stroke 、 Brain ischemia 、 Cerebral infarction 、 Chronic stroke
摘要: Stem cell therapy (SCT) has been proposed for the treatment of neurological disorders. Although there is insufficient clinical evidence to support its efficacy, unproven SCTs are being performed worldwide. In this study, we investigated perspectives and expectations chronic ischemic stroke patients physicians about SCTs. A total 250 were interviewed at 4 hospitals. Structured open closed questions SCT asked by trained interviewers using conventional in-person method. addition, stroke-related randomly via an e-mail questionnaire. Of (mean 63 years, 70% male), 121 (46%) responded that they wanted receive in spite unknown side effects. Around 60% anticipated physical, emotional, psychological improvement after SCT, 158 (63%) believed might prevent strokes. However, had much lower effectiveness ...
core.ac.uk 
sci-hub.se 参考文章(22)
G. Gaskell, COMMUNICATION: Enhanced: Social Values and the Governance of Science Science. ,vol. 310, pp. 1908- 1909 ,(2005) , 10.1126/SCIENCE.1119444
M. Enserink, Selling the Stem Cell Dream Science. ,vol. 313, pp. 160- 163 ,(2006) , 10.1126/SCIENCE.313.5784.160
Byung-Woo Yoon, Young Seo Kim, Sang-Soon Park, Hee-Joon Bae, Ji Hoe Heo, Sun U. Kwon, Byung-Chul Lee, Seung-Hoon Lee, Chang Wan Oh, Public Awareness of Stroke in Korea A Population-Based National Survey Stroke. ,vol. 43, pp. 1146- 1149 ,(2012) , 10.1161/STROKEAHA.111.638460
H Liu, O Honmou, K Harada, K Nakamura, K Houkin, H Hamada, JD Kocsis, NEUROPROTECTION BY PLGF GENE-MODIFIED HUMAN MESENCHYMAL STEM CELLS AFTER CEREBRAL ISCHAEMIA Brain. ,vol. 129, pp. 2734- 2745 ,(2006) , 10.1093/BRAIN/AWL207
T. Nomura, O. Honmou, K. Harada, K. Houkin, H. Hamada, J.D. Kocsis, I.V. Infusion of brain-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat Neuroscience. ,vol. 136, pp. 161- 169 ,(2005) , 10.1016/J.NEUROSCIENCE.2005.06.062
Pär Thored, Andreas Arvidsson, Emanuele Cacci, Henrik Ahlenius, Therése Kallur, Vladimer Darsalia, Christine T. Ekdahl, Zaal Kokaia, Olle Lindvall, Persistent production of neurons from adult brain stem cells during recovery after stroke Stem Cells. ,vol. 24, pp. 739- 747 ,(2006) , 10.1634/STEMCELLS.2005-0281
Edna Einsiedel, Shainur Premji, Rose Geransar, Noelle C. Orton, Thushaanthini Thavaratnam, Laura K. Bennett, Diversity in public views toward stem cell sources and policies. Stem Cell Reviews and Reports. ,vol. 5, pp. 102- 107 ,(2009) , 10.1007/S12015-009-9063-3
Douglas Kondziolka, Gary K. Steinberg, Lawrence Wechsler, Carolyn C. Meltzer, Elaine Elder, James Gebel, Sharon DeCesare, Tudor Jovin, Ross Zafonte, Jonathan Lebowitz, John C. Flickinger, David Tong, Michael P. Marks, Catriona Jamieson, Desiree Luu, Teresa Bell-Stephens, Jeffrey Teraoka, Neurotransplantation for patients with subcortical motor stroke: a phase 2 randomized trial. Journal of Neurosurgery. ,vol. 103, pp. 38- 45 ,(2005) , 10.3171/JNS.2005.103.1.0038
O. Lindvall, I. Hyun, Medical innovation versus stem cell tourism. Science. ,vol. 324, pp. 1664- 1665 ,(2009) , 10.1126/SCIENCE.1171749
Jin Soo Lee, Ji Man Hong, Gyeong Joon Moon, Phil Hyu Lee, Young Hwan Ahn, Oh Young Bang, A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke. Stem Cells. ,vol. 28, pp. 1099- 1106 ,(2010) , 10.1002/STEM.430