Haptoglobin serum concentration is a suitable biomarker to assess the efficacy of a feed additive in pigs

作者: Y. Saco , L. Fraile , M. Giménez , R. Pato , M. Montoya

DOI: 10.1017/S1751731109991418

关键词: Acute-phase proteinBiomarker (medicine)Attenuated vaccineFeed additiveImmunologyInterleukinHaptoglobinAnimal scienceBiologyVaccinationHerd

摘要: Levels of haptoglobin and Pig-major acute phase protein (MAP) were analysed in animals from a commercial herd receiving or not diet enriched with an additive. The group the additive exhibited decrease after 3 weeks, suggesting that better health status has been established, together improvement total body weight average daily gain. In contrast, Pig-MAP does significantly change under these conditions. Aujeszky live modified vaccination, which is compulsory Spain, did cause significant increment serum concentration although it affect Pig-MAP. response proteins to vaccination was similar both control additive-treated groups. Interleukins (IL)-1β IL-6 below detection limits most animals. conclusion, this study shows concentration, but Pig-MAP, good biomarker monitorize production parameters for monitoring vaccine pigs reared standard

参考文章(33)
Joan Weenberg, Elisa Crisci, María Montoya, Santi Bernaus, Lorenzo J. Fraile, Lorenzo Mendoza, Montse Armadans, Lara Ruiz, Effect of treatment with phytosterols in three herds with porcine respiratory disease complex. Journal of Swine Health and Production. ,vol. 17, pp. 32- 41 ,(2009)
D J Schaeffer, D P Bane, T E Eurell, W F Hall, Serum haptoglobin concentration as an indicator of weight gain in pigs. Canadian Journal of Veterinary Research-revue Canadienne De Recherche Veterinaire. ,vol. 56, pp. 6- 9 ,(1992)
P. David Eckersall, Susan Duthie, Mathilda J.M. Toussaint, Erik Gruys, Peter Heegaard, Maria Alava, Cornelia Lipperheide, Francois Madec, Standardization of Diagnostic Assays for Animal Acute Phase Proteins Advances in Veterinary Medicine. ,vol. 41, pp. 643- 655 ,(1999) , 10.1016/S0065-3519(99)80050-0
H. Kothalawala, M.J.M. Toussaint, E. Gruys, An overview of swine influenza. Veterinary Quarterly. ,vol. 28, pp. 45- 53 ,(2006) , 10.1080/01652176.2006.9695207
P.David Eckersall, John W Gow, Christopher McComb, Barbara Bradley, Jean Rodgers, Maxwell Murray, Peter G.E Kennedy, Cytokines and the acute phase response in post-treatment reactive encephalopathy of Trypanosoma brucei brucei infected mice. Parasitology International. ,vol. 50, pp. 15- 26 ,(2001) , 10.1016/S1383-5769(00)00065-9
Matilde Piñeiro, Carlos Piñeiro, Rakel Carpintero, Joaquín Morales, Fiona M. Campbell, P. David Eckersall, Mathilda J.M. Toussaint, Fermín Lampreave, Characterisation of the pig acute phase protein response to road transport. Veterinary Journal. ,vol. 173, pp. 669- 674 ,(2007) , 10.1016/J.TVJL.2006.02.006
N.S. Sorensen, C. Tegtmeier, L.O. Andresen, M. Piñeiro, M.J.M. Toussaint, F.M. Campbell, F. Lampreave, P.M.H. Heegaard, The porcine acute phase protein response to acute clinical and subclinical experimental infection with Streptococcus suis. Veterinary Immunology and Immunopathology. ,vol. 113, pp. 157- 168 ,(2006) , 10.1016/J.VETIMM.2006.04.008
E. Gruys, M.J.M. Toussaint, N. Upragarin, EDEREN A.M. Van, A.A. Adewuyi, D. Candiani, T.K.A. Nguyen, J. Sabeckiene, Acute phase reactants, challenge in the near future of animal production and veterinary medicine. Journal of Zhejiang University-science B. ,vol. 6, pp. 941- 947 ,(2005) , 10.1631/JZUS.2005.B0941