Profound hyponatraemia following a tramadol overdose.

摘要: Sir, Hyponatraemia is a common electrolyte disturbance associated with prolonged hospitalization and increased mortality. Among numerous aetiologies, tramadol not routinely included in the list of causative medications. This case highlights an important biochemical side effect, symptoms that may be easily overlooked without appropriate investigation. A 56-year-old man presented to hospital 12 h after intentional overdose 60 (50 mg) tablets 20 co-dydramol (10/500) tablets. The past medical history COPD, treated spiriva seretide inhalers. There was no other current or previous medication use. On examination, he drowsy pinpoint pupils respiratory rate six breaths per minute. Blood pressure 135/80 mmHg heart 110 beats …