Formation and reactivity of dilithiated N-furfurylbenzamides. Synthesis of α-substituted N-furfurylbenzamides
作者： Kosei Ohno , Minoru Machida
DOI: 10.1016/S0040-4039(01)93021-7
关键词: Electrophile 、 Lithium diisopropylamide 、 Tetrahydrofuran 、 Organic chemistry 、 Reactivity (chemistry) 、 Chemistry
摘要: Abstract Dianion 3 can be efficiently and regioselectively generated from N-furfurylbenzamide with lithium diisopropylamide/tetrahydrofuran/−78°C react various electrophiles to give α-substituted derivatives in good yields.
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