Characterization of Acinetobacter baumannii Clinical Isolates Carrying blaOXA-23 Carbapenemase and 16S rRNA Methylase armA genes in Yemen
作者： Sofiane Bakour , Samer Ahmed Alsharapy , Abdelaziz Touati , Jean-Marc Rolain
关键词: Amikacin 、 Imipenem 、 Biology 、 Multilocus sequence typing 、 Antibiotics 、 Microbiology 、 Ciprofloxacin 、 Aminoglycoside 、 Carbapenem 、 Acinetobacter baumannii
摘要: Purpose: The aim of this study was to investigate the molecular support resistance carbapenems, aminoglycosides, and fluoroquinolones in Acinetobacter baumannii clinical isolates collected from Yemen hospital. Methods: Three A. were isolated February 2013 three patients hospitalized at Al-Thawra University Hospital Sana'a, Yemen. Antibiotic susceptibility testing performed using disk diffusion E-test methods. Carbapenemase production carried out by modified Hodge test (MHT) imipenem–ethylenediaminetetraacetic acid (EDTA) Carbapenem, aminoglycoside, fluoroquinolone determinants studied polymerase chain reaction sequencing. epidemiological relatedness strains multilocus sequence typing (MLST). Results: resistant almost all antibiotics tested with very high imipenem, amikacin, ciprofloxacin minimum inhibitory concentrations (>32, >256, >32 mg/L, respectively)....
sci-hub.se 参考文章(38)
Seon Ju Jang, Sang Hee Lee, Kyungwon Lee, Dongeun Young, Seok Hoon Jeong, Kwang Hoon Sung, Ki Suk Yang, Kwang Ok Park, Il Kwon Bae, Seung Ghyu Sohn, Young Jun An, Outbreaks of imipenem-resistant Acinetobacter baumannii producing carbapenemases in Korea. Journal of Microbiology. ,vol. 44, pp. 423- 431 ,(2006)
P. Mugnier, L. Poirel, M. Pitout, P. Nordmann, Carbapenem‐resistant and OXA‐23‐producing Acinetobacter baumannii isolates in the United Arab Emirates Clinical Microbiology and Infection. ,vol. 14, pp. 879- 882 ,(2008) , 10.1111/J.1469-0691.2008.02056.X
A. Ghazawi, Á. Sonnevend, R.A. Bonnin, L. Poirel, P. Nordmann, R. Hashmey, T.A. Rizvi, M. B Hamadeh, T. Pál, NDM‐2 carbapenemase‐producing Acinetobacter baumannii in the United Arab Emirates Clinical Microbiology and Infection. ,vol. 18, ,(2012) , 10.1111/J.1469-0691.2011.03726.X
M. Aly, H. T. Tayeb, S. M. Al Johani, E. J. Alyamani, F. Aldughaishem, I. Alabdulkarim, H. H. Balkhy, Genetic diversity of OXA-51-like genes among multidrug-resistant Acinetobacter baumannii in Riyadh, Saudi Arabia European Journal of Clinical Microbiology & Infectious Diseases. ,vol. 33, pp. 1223- 1228 ,(2014) , 10.1007/S10096-014-2068-0
Lenie Dijkshoorn, Alexandr Nemec, Harald Seifert, An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii Nature Reviews Microbiology. ,vol. 5, pp. 939- 951 ,(2007) , 10.1038/NRMICRO1789
Ignasi Roca, Paula Espinal, Xavier Vila-Farrés, Jordi Vila, None, The Acinetobacter baumannii Oxymoron: Commensal Hospital Dweller Turned Pan-Drug-Resistant Menace. Frontiers in Microbiology. ,vol. 3, pp. 148- ,(2012) , 10.3389/FMICB.2012.00148
P. D. Mugnier, K. M. Bindayna, L. Poirel, P. Nordmann, Diversity of plasmid-mediated carbapenem-hydrolysing oxacillinases among carbapenem-resistant Acinetobacter baumannii isolates from Kingdom of Bahrain Journal of Antimicrobial Chemotherapy. ,vol. 63, pp. 1071- 1073 ,(2009) , 10.1093/JAC/DKP052
Meriem Touati, Seydina M. Diene, Abdelkarim Racherache, Mazouz Dekhil, Abdelghani Djahoudi, Jean-Marc Rolain, Emergence of blaOXA-23 and blaOXA-58 carbapenemase-encoding genes in multidrug-resistant Acinetobacter baumannii isolates from University Hospital of Annaba, Algeria. International Journal of Antimicrobial Agents. ,vol. 40, pp. 89- 91 ,(2012) , 10.1016/J.IJANTIMICAG.2012.03.017
Ioannis K. Neonakis, Demetrios A. Spandidos, Efthimia Petinaki, Confronting multidrug-resistant Acinetobacter baumannii: a review International Journal of Antimicrobial Agents. ,vol. 37, pp. 102- 109 ,(2011) , 10.1016/J.IJANTIMICAG.2010.10.014
N.A. Al-Sweih, M. Al-Hubail, V.O. Rotimi, Three distinct clones of carbapenem-resistant Acinetobacter baumannii with high diversity of carbapenemases isolated from patients in two hospitals in Kuwait Journal of Infection and Public Health. ,vol. 5, pp. 102- 108 ,(2012) , 10.1016/J.JIPH.2011.11.004