CRISPR/Cas9 mediated sequential editing of genes critical for ookinete motility in Plasmodium yoelii.

作者: Cui Zhang , Han Gao , Zhenke Yang , Yuanyuan Jiang , Zhenkui Li

DOI: 10.1016/J.MOLBIOPARA.2016.12.010

关键词: PlasmidCas9Plasmodium falciparumBiologyCRISPRGeneGenome editingPlasmodium yoeliiGenomeGenetics

摘要: … compared the growth rates of both … CRISPR/Cas9 complex requires transient expression of Cas9/sgRNA and hDHFR from the pYC vector without integration of the drug resistance gene …

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