Detection of EGFR mutations in plasma DNA from lung cancer patients by mass spectrometry genotyping is predictive of tumor EGFR status and response to EGFR inhibitors
作者： Marie Brevet , Melissa L. Johnson , Christopher G. Azzoli , Marc Ladanyi
DOI: 10.1016/J.LUNGCAN.2010.10.014
关键词: Plasma dna 、 Egfr mutation 、 Lung cancer 、 Adenocarcinoma 、 EGFR inhibitors 、 Genotyping 、 Medicine 、 Genotype 、 Cancer research 、 Erlotinib Hydrochloride
摘要: … EGFR mutations now guide the clinical use of EGFR-targeted therapy in lung cancer. However, standard EGFR mutation … a mutant-enriched PCR (ME-PCR) to detect EGFR mutations in …
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