Plasma adiponectin and pregnancy-induced insulin resistance.

摘要: Lindsay et al. (1) recently published an article in Diabetes Care that claims adiponectin is present the cord blood of offspring diabetic and nondiabetic pregnant mothers its level does not correlate with their birth weight skinfold thickness. Our data, obtained from a case-control study women gestational diabetes mellitus (GDM), further support role insulin resistance. We observed significantly decreased plasma levels (7.55 ± 2.04 μg/ml [means SD]) using radioimmunoassay (Linco Research, St. Charles, MO) (intra-assay precision coefficient variation [CV] 3.86%, interassay CV 8.47%) 30 GDM, all whom were treated (aged 28.12 2.71 years, age 27.35 6.15 weeks), compared 40 tested oral glucose tolerance test (OGTT) (total group 9.91 3.32, P < 0.01, Mann-Whitney, aged 26.91 2.65 …