Risks of combined alcohol/medication use in older adults.

摘要: Abstract Background: Many older adults (ie, those aged ≥65 years) drink alcohol and use medications that may be harmful when consumed together. Objective: This article reviews the literature on medication interactions, with a focus adults. Methods: Relevant articles were identified through search of MEDLINE International Pharmaceutical Abstracts (1966–August 2006) for English-language articles. The following medical subject headings key words used: diseases worsened by , metabolism, absorption, distribution . Additional manual reference lists articles, review textbooks, personal sources. Results: take interact negatively alcohol. Some these interactions are due to age-related changes in distribution, metabolism medications. Others disulfiram-like reactions observed some medications, exacerbation therapeutic effects adverse combined alcohol, alcohol's interference effectiveness Conclusions: Older who at risk variety consequences depending amount type consumed. It is important clinicians know how much their patients drinking able effectively assess risks counsel them about safe Similarly, it understand potential avoid myriad problems possible unsafe substances.