Classification of acute encephalopathy in respiratory syncytial virus infection

摘要: Infection with respiratory syncytial virus (RSV) is known to be associated central nervous system symptoms such as convulsions. We investigated cytokines, nitrogen oxide (NO)x, and the viral genome in cerebrospinal fluid (CSF) obtained from children RSV infection-related convulsions or compared data type of encephalopathy. Of nine patients enrolled (six boys three girls; aged 10 days–3 years), one metabolic error, five excitotoxicity, cytokine storm, two hypoxia cases were found. The presented unilateral convulsions, generalized following cardiopulmonary arrest, apnea, nuchal rigidity. In all patients, a rapid check for nasal was positive. (subgroup A) detected CSF patients; hypoxic encephalopathy negative genome. interleukin (IL)-6 levels high only excitotoxicity storm NOx subject cases. type, significantly higher than those control other groups. level may become an important parameter diagnosis classification acute RSV. Strategies treat each encephalopathy, targeting cytokines free radicals, should established.