Production of Biologically Active Recombinant Human Lactoferrin in Aspergillus Oryzae
作者： Pauline P. Ward , Jing-Y. Lo , Mairead Duke , Gregory S. May , Denis R. Headon
DOI: 10.1038/NBT0792-784
关键词: Aspergillus oryzae 、 Gene expression 、 Lactoferrin 、 Microbiology 、 Biochemistry 、 Recombinant DNA 、 Secretion 、 Glycoprotein 、 Biology 、 Heterologous 、 Complementary DNA 、 Biotechnology 、 Molecular medicine 、 Applied Microbiology and Biotechnology 、 Bioengineering 、 Biomedical engineering
摘要: … of recombinant human lactoferrin in Aspergillus oryzae. Expression of human lactoferrin (… IgG directed against human lactoferrin detected a 78 kD protein corresponding to the size of …
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R Oseas, HH Yang, RL Baehner, LA Boxer, Lactoferrin: a promoter of polymorphonuclear leukocyte adhesiveness. Blood. ,vol. 57, pp. 939- 945 ,(1981) , 10.1182/BLOOD.V57.5.939.939
E. Boel, M.T. Hansen, I. Hjort, I. Høegh, N.P. Fiil, Two different types of intervening sequences in the glucoamylase gene from Aspergillus niger. The EMBO Journal. ,vol. 3, pp. 1581- 1585 ,(1984) , 10.1002/J.1460-2075.1984.TB02014.X
Jennifer Van Brunt, Fungi: The Perfect Hosts? Nature Biotechnology. ,vol. 4, pp. 1057- 1062 ,(1986) , 10.1038/NBT1286-1057
Colin D Rasmussen, Raylene L Means, Kun Ping Lu, Gregory S May, Anthony R Means, Characterization and expression of the unique calmodulin gene of Aspergillus nidulans. Journal of Biological Chemistry. ,vol. 265, pp. 13767- 13775 ,(1990) , 10.1016/S0021-9258(18)77415-2
MR Schlabach, GW Bates, The synergistic binding of anions and Fe3+ by transferrin. Implications for the interlocking sites hypothesis. Journal of Biological Chemistry. ,vol. 250, pp. 2182- 2188 ,(1975) , 10.1016/S0021-9258(19)41699-2
Jennifer Van Brunt, Arthur Klausner, None, A Direct Route to Biotech Directories Nature Biotechnology. ,vol. 4, pp. 962- 967 ,(1986) , 10.1038/NBT1186-962
Shuichi Hashizume, Kazuhiko Kuroda, Hiroki Murakami, Identification of lactoferrin as an essential growth factor for human lymphocytic cell lines in serum-free medium. Biochimica et Biophysica Acta. ,vol. 763, pp. 377- 382 ,(1983) , 10.1016/0167-4889(83)90099-X
Pekka Vilja, Kai Krohn, Pentti Tuohimaa, A rapid and sensitive non-competitive avidin-biotin assay for lactoferrin. Journal of Immunological Methods. ,vol. 76, pp. 73- 83 ,(1985) , 10.1016/0022-1759(85)90482-X
Tove Christensen, Helle Woeldike, Esper Boel, Steen B. Mortensen, Kirsten Hjortshoej, Lars Thim, Mogens T. Hansen, High Level Expression of Recombinant Genes in Aspergillus Oryzae Nature Biotechnology. ,vol. 6, pp. 1419- 1422 ,(1988) , 10.1038/NBT1288-1419
P. L. Masson, J. F. Heremans, E. Schonne, LACTOFERRIN, AN IRON-BINBING PROTEIN NI NEUTROPHILIC LEUKOCYTES Journal of Experimental Medicine. ,vol. 130, pp. 643- 658 ,(1969) , 10.1084/JEM.130.3.643