The clinical application of 4D 18F-FDG PET/CT on gross tumor volume delineation for radiotherapy planning in esophageal squamous cell cancer
作者： Y.-C. Wang , T.-C. Hsieh , C.-Y. Yu , K.-Y. Yen , S.-W. Chen
DOI: 10.1093/JRR/RRS009
关键词: Contouring 、 Radiation therapy 、 Four-Dimensional Computed Tomography 、 Radiology 、 Squamous cell cancer 、 Esophageal cancer 、 Nuclear medicine 、 Gross tumor volume 、 Fdg pet ct 、 Positron emission tomography 、 Medicine
摘要: A combination of four-dimensional computed tomography with 18 F-fluorodeoxyglucose positron emission (4D CT-FDG PET) was used to delineate gross tumor volume (GTV) in esophageal cancer (EC). Eighteen patients EC were prospectively enrolled. Using 4D images taken during the respiratory cycle, average CT image phase fused FDG PET order analyze optimal standardized uptake values (SUV) or threshold. PET-based GTV (GTVPET) determined eight different threshold methods using auto-contouring function on workstation. The difference ratio (VR) and conformality index (CI) between GTVPET CT-based (GTVCT )w as investigated. sets via automatic co-registrations available for 12 13 GTVCT values. decision coefficient (R 2 ) length at levels SUV 2.5, 20% 25% 0.79, 0.65 0.54, respectively. mean 29.41 ± 19.14 ml. VR ranged from 0.30 1.48. 0.98, close 1, 2.5. CI 0.28 0.58. best (0.58) 2.5 (0.57). has potential assist contouring GTV. setting achieves correlation length, VR, 4D-PET/CT images.
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Xavier Geets, Max Lonneux, Vincent Grégoire, Sarah Roels, Karin Haustermans, PET-based treatment planning in radiotherapy: a new standard? The Journal of Nuclear Medicine. ,vol. 48, ,(2007)
Marcelo Mamede, Georges El Fakhri, Paula Abreu-e-Lima, William Gandler, Vânia Nosé, Victor H. Gerbaudo, Pre-operative estimation of esophageal tumor metabolic length in FDG-PET images with surgical pathology confirmation. Annals of Nuclear Medicine. ,vol. 21, pp. 553- 562 ,(2007) , 10.1007/S12149-007-0040-0
Valentino Bettinardi, Maria Picchio, Nadia Di Muzio, Luigi Gianolli, Maria Carla Gilardi, Cristina Messa, Detection and compensation of organ/lesion motion using 4D-PET/CT respiratory gated acquisition techniques Radiotherapy and Oncology. ,vol. 96, pp. 311- 316 ,(2010) , 10.1016/J.RADONC.2010.07.014
Jinming Yu, Xinke Li, Ligang Xing, Dianbin Mu, Zheng Fu, Xiaorong Sun, Xiangyu Sun, Guoren Yang, Baijiang Zhang, Xindong Sun, C. Clifton Ling, COMPARISON OF TUMOR VOLUMES AS DETERMINED BY PATHOLOGIC EXAMINATION AND FDG-PET/CT IMAGES OF NON-SMALL-CELL LUNG CANCER: A PILOT STUDY International Journal of Radiation Oncology Biology Physics. ,vol. 75, pp. 1468- 1474 ,(2009) , 10.1016/J.IJROBP.2009.01.019
Christina T. Muijs, Jannet C. Beukema, Jan Pruim, Veronique E. Mul, Henk Groen, John Th. Plukker, Johannes A. Langendijk, A systematic review on the role of FDG-PET/CT in tumour delineation and radiotherapy planning in patients with esophageal cancer Radiotherapy and Oncology. ,vol. 97, pp. 165- 171 ,(2010) , 10.1016/J.RADONC.2010.04.024
Bernhard Berger, Claus Belka, Evidence-based radiation oncology: oesophagus. Radiotherapy and Oncology. ,vol. 92, pp. 276- 290 ,(2009) , 10.1016/J.RADONC.2009.02.019
Vinai Gondi, Kristin Bradley, Minesh Mehta, Andy Howard, Deepak Khuntia, Mark Ritter, Wolfgang Tomé, Impact of hybrid fluorodeoxyglucose positron-emission tomography/computed tomography on radiotherapy planning in esophageal and non–small-cell lung cancer International Journal of Radiation Oncology Biology Physics. ,vol. 67, pp. 187- 195 ,(2007) , 10.1016/J.IJROBP.2006.09.033
Kailiang Wu, Yee C. Ung, Jennifer Hornby, Marc Freeman, David Hwang, Ming S. Tsao, Max Dahele, Gail Darling, Donna E. Maziak, Romeo Tirona, Kathy Mah, C. Shun Wong, PET CT thresholds for radiotherapy target definition in non-small-cell lung cancer: how close are we to the pathologic findings? International Journal of Radiation Oncology Biology Physics. ,vol. 77, pp. 699- 706 ,(2010) , 10.1016/J.IJROBP.2009.05.028
Theodore S. Hong, Joseph H. Killoran, Marcelo Mamede, Harvey J. Mamon, Impact of manual and automated interpretation of fused PET/CT data on esophageal target definitions in radiation planning. International Journal of Radiation Oncology Biology Physics. ,vol. 72, pp. 1612- 1618 ,(2008) , 10.1016/J.IJROBP.2008.07.061
Wen Yu, Xiao-Long Fu, Ying-Jian Zhang, Jia-Qing Xiang, Lei Shen, Guo-Liang Jiang, Joe Y. Chang, GTV spatial conformity between different delineation methods by 18FDG PET/CT and pathology in esophageal cancer. Radiotherapy and Oncology. ,vol. 93, pp. 441- 446 ,(2009) , 10.1016/J.RADONC.2009.07.003