PET-based treatment planning in radiotherapy: a new standard?
作者： Xavier Geets , Max Lonneux , Vincent Grégoire , Sarah Roels , Karin Haustermans
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摘要: Molecular imaging, in particular, PET, has brought an additional dimension to management for patients with cancer. 18F-FDG, which is the most widely available tracer, been shown be of value selection target volumes radiation oncology. Depending on its sensitivity and specificity, 18F-FDG influence non-small cell lung cancers (NSCLC) or esophageal tumors. On other hand, tumors such as head neck squamous carcinomas (HNSCC) rectal carcinomas, convincing data volume are still lacking. For delineation, given that adequate method used segmentation, added demonstrated HNSCC NSCLC. both types tumors, modifications delineation translated into differences dose distribution compared results CT scan-based plans. Studies progress Novel markers tumor hypoxia proliferation have potential modify volumes, allowing "dose painting" selected subvolumes. Finally, variations viability during radiotherapy also under intense investigation, potentially paving way so-called "theragnostic" adaptive treatment. This review discusses how PET/CT might current state art planning.
参考文章(96)
Maroldi R, Maculotti P, Farina D, Chiesa A, Battaglia G, Tumours of the oropharynx and oral cavity: perineural spread and bone invasion. Journal belge de radiologie. ,vol. 82, pp. 294- 300 ,(1999)
Jacques Bernier, Eric J. Hall, Amato Giaccia, Radiation oncology: a century of achievements Nature Reviews Cancer. ,vol. 4, pp. 737- 747 ,(2004) , 10.1038/NRC1451
Tatsuo Ido, Kazuo Kubota, Masao Tada, Roko Kubota, Susumu Yamada, Nobuaki Tamahashi, Microautoradiographic study for the differentiation of intratumoral macrophages, granulation tissues and cancer cells by the dynamics of fluorine-18-fluorodeoxyglucose uptake. The Journal of Nuclear Medicine. ,vol. 35, pp. 104- 112 ,(1994)
Zohar Keidar, Abraham Kuten, Ludmila Guralnik, Nikolai Yefremov, Alex Frenkel, Diana Gaitini, Ora Israel, Rachel Bar-Shalom, Hernan Altman, Clinical Performance of PET/CT in Evaluation of Cancer: Additional Value for Diagnostic Imaging and Patient Management The Journal of Nuclear Medicine. ,vol. 44, pp. 1200- 1209 ,(2003)
C. Kruschke, R. J. Kau, Norbert Avril, C. Wagner-Manslau, C. Laubenbacher, M. Schwaiger, S. Ziegler, D. Saumweber, M. Herz, W. Arnold, Comparison of Fluorine-18-Fluorodeoxyglucose PET, MRI and Endoscopy for Staging Head and Neck Squamous-Cell Carcinomas The Journal of Nuclear Medicine. ,vol. 36, pp. 1747- 1757 ,(1995)
Luc Boucher, François Bénard, Roger Lecomte, Serge Rodrigue, Respiratory Gating for 3-Dimensional PET of the Thorax: Feasibility and Initial Results The Journal of Nuclear Medicine. ,vol. 45, pp. 214- 219 ,(2004)
Yoshiharu Yonekura, Hideyuki Taniuchi, Junji Konishi, Akira Yokoyama, Hiroshi Ohtani, Yasuhisa Fujibayashi, Copper-62-ATSM: A New Hypoxia Imaging Agent with High Membrane Permeability and Low Redox Potential The Journal of Nuclear Medicine. ,vol. 38, pp. 1155- 1160 ,(1997)
J F Vansteenkiste, S G Stroobants, P R De Leyn, P J Dupont, J Bogaert, A Maes, G J Deneffe, K L Nackaerts, J A Verschakelen, T E Lerut, L A Mortelmans, M G Demedts, Lymph node staging in non-small-cell lung cancer with FDG-PET scan: a prospective study on 690 lymph node stations from 68 patients. Journal of Clinical Oncology. ,vol. 16, pp. 2142- 2149 ,(1998) , 10.1200/JCO.1998.16.6.2142
Lee P. Adler, Michael Rodriguez, Peter F. Faulhaber, Fadi W. Abdul-Karim, Floro Miraldi, Peter G. Rose, Positron Emission Tomography for Evaluating Para-aortic Nodal Metastasis in Locally Advanced Cervical Cancer Before Surgical Staging: A Surgicopathologic Study Journal of Clinical Oncology. ,vol. 17, pp. 41- 41 ,(1999) , 10.1200/JCO.1999.17.1.41
Barbara J. Fueger, Osman Ratib, Martin S. Allen-Auerbach, Johannes Czernin, Michael E. Phelps, Benjamin S. Halpern, Jong-Ho Kim, Wolfgang A. Weber, Joel R. Hecht, Comparison Between 18F-FDG PET, In-Line PET/CT, and Software Fusion for Restaging of Recurrent Colorectal Cancer The Journal of Nuclear Medicine. ,vol. 46, pp. 587- 595 ,(2005)