Molecular Characterization and Patient Outcome of Melanoma Nodal Metastases and an Unknown Primary Site
作者： Aleksandra Gos , Monika Jurkowska , Alexander van Akkooi , Caroline Robert , Hanna Kosela-Paterczyk
DOI: 10.1245/S10434-014-3799-Y
关键词: Medicine 、 Internal medicine 、 NODAL 、 Surgical oncology 、 Melanoma 、 Clinical manifestation 、 Pathology 、 Unknown primary 、 Oncology 、 Neuroblastoma RAS viral oncogene homolog
摘要: Background Melanoma of unknown primary site (MUP) is not a completely understood entity with nodal metastases as the most common first clinical manifestation. The aim this multicentric study was to assess frequency and type oncogenic BRAF/NRAS/KIT mutations in MUP clinically detected relation clinicopathologic features outcome.
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