Characterization of plaque components and vulnerability with intravascular ultrasound elastography.

摘要: Intravascular ultrasound elastography is a method for measuring the local elastic properties using intravascular (IVUS). The of different tissues within atherosclerotic plaque are measured through strain. Knowledge these useful guiding interventional procedures (balloon dilatation, ablation) and detection vulnerable plaque. In last decade, several groups have applied intravascularly with various levels success. this paper, approaches research will be discussed. focus on our approach to application elastography. Elastograms were acquired in vitro vivo relative displacements between IVUS images at two pressure 30 MHz mechanical or 20 array echo catheter. These estimated from time shift gated radiofrequency signals cross-correlation algorithms interpolation around peak. Experiments gel-based phantoms mimicking vessels demonstrated capability identify soft hard independently echogenicity contrast. experiments human arteries potential types based their properties. plaques could not identified image alone. revealed that reproducible elastograms obtained near end-diastole. Partial validation echogram was performed. provides information frequently unavailable inconclusive which may therefore assist diagnosis treatment disease.