Modified PLGA–PEG–PLGA thermosensitive hydrogels with suitable thermosensitivity and properties for use in a drug delivery system

作者: Puxiu Wang , Wei Chu , Xuezhi Zhuo , Yu Zhang , Jingxin Gou

DOI: 10.1039/C6TB02158A

关键词: Window WidthSelf-healing hydrogelsPlga peg plgaBiomedical engineeringSurgical proceduresDrug deliveryCopolymerMaterials sciencePolymer chemistryBiocompatible materialTarget site

摘要: … , PLGA/PEG block thermoreversible gelling polymers are the most extensively investigated ones due to the biodegradability and biocompatibility of PLGA. Such PLGA/PEG block …

参考文章(158)
Zhenhua Li, Wen Ning, Jumei Wang, Augustine Choi, Pui-Yan Lee, Pradeep Tyagi, Leaf Huang, Controlled gene delivery system based on thermosensitive biodegradable hydrogel. Pharmaceutical Research. ,vol. 20, pp. 884- 888 ,(2003) , 10.1023/A:1023887203111
Rita Palmeira-de-Oliveira, Ana Palmeira-de-Oliveira, José Martinez-de-Oliveira, New strategies for local treatment of vaginal infections. Advanced Drug Delivery Reviews. ,vol. 92, pp. 105- 122 ,(2015) , 10.1016/J.ADDR.2015.06.008
Xiaoyan Yang, Hoang M. Trinh, Vibhuti Agrahari, Ye Sheng, Dhananjay Pal, Ashim K. Mitra, Nanoparticle-Based Topical Ophthalmic Gel Formulation for Sustained Release of Hydrocortisone Butyrate. Aaps Pharmscitech. ,vol. 17, pp. 294- 306 ,(2016) , 10.1208/S12249-015-0354-5
Young Jin Kim, Suna Choi, Jae Joon Koh, Minhyung Lee, Kyung Soo Ko, Sung Wan Kim, Controlled release of insulin from injectable biodegradable triblock copolymer. Pharmaceutical Research. ,vol. 18, pp. 548- 550 ,(2001) , 10.1023/A:1011074915438
Thomas P. Johnston, Monika A. Punjabi, Christopher J. Froelich, Sustained delivery of interleukin-2 from a poloxamer 407 gel matrix following intraperitoneal injection in mice. Pharmaceutical Research. ,vol. 9, pp. 425- 433 ,(1992) , 10.1023/A:1015815624334
N. Marina, S. Bielack, J. Whelan, S. Smeland, M. Krailo, M. R. Sydes, T. Butterfass-Bahloul, G. Calaminus, M. Bernstein, International collaboration is feasible in trials for rare conditions: The EURAMOS experience Cancer treatment and research. ,vol. 152, pp. 339- 353 ,(2007) , 10.1007/978-1-4419-0284-9_18
Li Zhang, Wenjia Shen, Jiabin Luan, Dongxiao Yang, Gang Wei, Lin Yu, Weiyue Lu, Jiandong Ding, Sustained intravitreal delivery of dexamethasone using an injectable and biodegradable thermogel. Acta Biomaterialia. ,vol. 23, pp. 271- 281 ,(2015) , 10.1016/J.ACTBIO.2015.05.005
Hang T. Ta, Crispin R. Dass, Ian Larson, Peter F.M. Choong, Dave E. Dunstan, A chitosan hydrogel delivery system for osteosarcoma gene therapy with pigment epithelium-derived factor combined with chemotherapy Biomaterials. ,vol. 30, pp. 4815- 4823 ,(2009) , 10.1016/J.BIOMATERIALS.2009.05.035
Sibao Chen, Jagdish Singh, Controlled release of growth hormone from thermosensitive triblock copolymer systems: In vitro and in vivo evaluation. International Journal of Pharmaceutics. ,vol. 352, pp. 58- 65 ,(2008) , 10.1016/J.IJPHARM.2007.10.016
Sibao Chen, Robert Pieper, Dean C. Webster, Jagdish Singh, Triblock copolymers: synthesis, characterization, and delivery of a model protein. International Journal of Pharmaceutics. ,vol. 288, pp. 207- 218 ,(2005) , 10.1016/J.IJPHARM.2004.09.026