Overdiagnosis of Complete and Partial Hydatidiform Mole in Tubal Ectopic Pregnancies

摘要: Partial or complete hydatidiform mole (HM) affects approximately 1 in 500 to 1,000 pregnancies. Previous small series suggest that histopathologic diagnosis of HM may be difficult tubal ectopic The histopathology database a regional Trophoblastic Disease Unit was searched identify cases with referral HM, and the findings were reviewed. During study period (1986-2004 inclusive), there 132 cases. After central review by specialist histopathologists, final partial two, five, (not otherwise specified) one. definite made eight (6%) cases, significantly less than referred uterine curettage specimens, which 90% have confirmatory (Z = 12.9; p < 0.0001). No this developed persistent gestational trophoblastic disease, human chorionic gonadotropin concentration spontaneously returning normal. Ectopic pregnancies, where managed surgically, should submitted for examination; however, pathologist aware degree extravillus proliferation appear more florid compared evacuated products conception. Molar pregnancy only diagnosed when strict criteria regarding morphologic abnormalities previously described evacuation material are applied.