Sequential volume mapping for confirmation of negative growth in vestibular schwannomas treated by gamma knife radiosurgery

摘要: Object. The purpose of this study was to confirm, by using a sequential volume mapping (SVM) technique, that gamma knife radiosurgery (GKS) induces negative growth in vestibular schwannomas (VS). Methods. Over period 5 years, 126 small- medium-sized (< 15 cm3) VSs were treated microradiosurgical techniques within standard protocol. All patient data collected prospectively. Sequential magnetic resonance imaging performed every 6 months assess the tumor, based on specially developed GammaPlan software. mean follow-up duration 22 months. At least three SVM measurements obtained 91 patients and at four 62 patients. number for each 2.54. After GKS, following patterns change seen: 1) 57 showed transient increase with peak months, followed shrinkage. Four exhibited prolonged swelling beyond 24 Transient eventual shrinkage wer...