Outcomes of management for potential deceased donors.

作者: J.C. Jeong , M.G. Kim , H. Ro , Y.J. Kim , H.C. Park

DOI: 10.1016/J.TRANSPROCEED.2012.01.102

关键词: Risk factorAcute kidney injuryCardiopulmonary resuscitationInternal medicineBacteremiaKidneyMedicineOdds ratioDiabetes insipidusConfidence interval

摘要: Abstract Backgrounds Potential deceased donor management optimization is important for organ recovery maximization. Before optimization, the current state of and predictors require analysis. Methods We retrospectively analyzed procurement activity medical 2005 to 2010 potential brain death donors at Seoul National University Hospital. Results Of 316 contacts brain-dead donors, 129 (39.7%) patients were transferred team. Among causes transfer failure, issues related proper affected 33%. Expanded criteria 17.9% donors. Organ was successful in 111 (90.2%) A total 360 organs recovered, corresponding a mean 2.92 ± 1.37 per donor. The absence demand an cause failure among less transplanted organs. Brain death-related complications identified as follows: acute kidney injury (AKI), defined by AKI network criteria, occurred 19 (15.4%); cardiopulmonary resuscitation 5 (3.1%); bacteremia 12 (9.7%); thrombocytopenia 24 (19.5%); diabetes insipidus 42 (34.1%). significant independent risk factor both liver (odds ratio [OR] 0.147, 95% confidence interval [0.045, 0.473], P = .001; OR 0.096, [0.023, 0.392], .001, liver, respectively). Conclusions Both success rate remained low Korea. during failure.

参考文章(13)
E. E. Messersmith, C. Arrington, C. Alexander, J. P. Orlowski, R. Wolfe, Development of Donor Yield Models American Journal of Transplantation. ,vol. 11, pp. 2075- 2084 ,(2011) , 10.1111/J.1600-6143.2011.03639.X
Ravindra L Mehta, John A Kellum, Sudhir V Shah, Bruce A Molitoris, Claudio Ronco, David G Warnock, Adeera Levin, Acute Kidney Injury Network, None, Acute Kidney Injury Network: Report of an Initiative to Improve Outcomes in Acute Kidney Injury Critical Care. ,vol. 11, pp. 1- 8 ,(2007) , 10.1186/CC5713
O. Len, J. Gavaldà, M. Blanes, M. Montejo, R. San Juan, A. Moreno, J. Carratalà, J. de la Torre-Cisneros, G. Bou, E. Cordero, P. Muñoz, V. Cuervas-Mons, M. T. Alvarez, N. Borrell, J. Fortun, A. Pahissa, , Donor infection and transmission to the recipient of a solid allograft. American Journal of Transplantation. ,vol. 8, pp. 2420- 2425 ,(2008) , 10.1111/J.1600-6143.2008.02397.X
Richard Ugarte, Edward Kraus, Robert A. Montgomery, James F. Burdick, Lloyd Ratner, Mark Haas, Alan M. Hawxby, Seth J. Karp, Excellent outcomes after transplantation of deceased donor kidneys with high terminal creatinine and mild pathologic lesions. Transplantation. ,vol. 80, pp. 794- 800 ,(2005) , 10.1097/01.TP.0000173801.33878.BF
Robert A. Metzger, Francis L. Delmonico, Sandy Feng, Friedrich K. Port, James J. Wynn, Robert M. Merion, Expanded criteria donors for kidney transplantation. American Journal of Transplantation. ,vol. 3, pp. 114- 125 ,(2003) , 10.1034/J.1600-6143.3.S4.11.X
Darren J. Malinoski, Michael C. Daly, Madhukar S. Patel, Chrystal Oley-Graybill, Clarence E. Foster, Ali Salim, Achieving donor management goals before deceased donor procurement is associated with more organs transplanted per donor. Journal of Trauma-injury Infection and Critical Care. ,vol. 71, pp. 990- 996 ,(2011) , 10.1097/TA.0B013E31822779E5
John D. Rosendale, H. Myron Kauffman, Maureen A. McBride, Franki L. Chabalewski, Jonathan G. Zaroff, Edward R. Garrity, Francis L. Delmonico, Bruce R. Rosengard, Aggressive pharmacologic donor management results in more transplanted organs. Transplantation. ,vol. 75, pp. 482- 487 ,(2003) , 10.1097/01.TP.0000045683.85282.93
F. W. Selck, P. Deb, E. B. Grossman, Deceased Organ Donor Characteristics and Clinical Interventions Associated with Organ Yield American Journal of Transplantation. ,vol. 8, pp. 965- 974 ,(2008) , 10.1111/J.1600-6143.2008.02205.X
Sang Il Min, Seong Yup Kim, Yang Jin Park, Seung-Kee Min, Yon Su Kim, Curie Ahn, Sang Joon Kim, Jongwon Ha, Trends in deceased organ donation and utilization in Korea: 2000-2009. Journal of Korean Medical Science. ,vol. 25, pp. 1122- 1127 ,(2010) , 10.3346/JKMS.2010.25.8.1122
E. Rodrigo, E. Minambres, C. Pinera, J. Llorca, G. Fernandez-Fresnedo, A. Vallejo, J. Ruiz, J. Ruiz, M. Gago, M. Arias, Using RIFLE criteria to evaluate acute kidney injury in brain-deceased kidney donors Nephrology Dialysis Transplantation. ,vol. 25, pp. 1531- 1537 ,(2010) , 10.1093/NDT/GFP622