Co-delivery of Vascular Endothelial Growth Factor and Angiopoietin-1 Using Injectable Microsphere/Hydrogel Hybrid Systems for Therapeutic Angiogenesis
作者： Seung-Hwa Shin , Jangwook Lee , Dong-Gyun Ahn , Kuen Yong Lee
DOI: 10.1007/S11095-013-1076-6
关键词: Microsphere 、 Angiogenesis 、 VEGF receptors 、 Neovascularization 、 Cancer research 、 Therapeutic angiogenesis 、 Co delivery 、 Vascular endothelial growth factor 、 Chemistry 、 Angiopoietin-1 、 Biotechnology 、 Organic chemistry 、 Molecular medicine 、 Pharmacology (medical) 、 Pharmacology 、 Pharmaceutical Science
摘要: Purpose We hypothesized that combined delivery of vascular endothelial growth factor (VEGF) and angiopoietin-1 (Ang-1) using microsphere/hydrogel hybrid systems could enhance mature vessel formation compared with administration each alone.
springer.com
sci-hub.se 参考文章(36)
Lei Ye, Husnain Kh Haider, Shujia Jiang, Ru San Tan, Ruowen Ge, Peter K Law, Eugene KW Sim, None, Improved angiogenic response in pig heart following ischaemic injury using human skeletal myoblast simultaneously expressing VEGF165 and angiopoietin-1. European Journal of Heart Failure. ,vol. 9, pp. 15- 22 ,(2007) , 10.1016/J.EJHEART.2006.04.008
Kuen Yong Lee, David J. Mooney, ALGINATE: PROPERTIES AND BIOMEDICAL APPLICATIONS Progress in Polymer Science. ,vol. 37, pp. 106- 126 ,(2012) , 10.1016/J.PROGPOLYMSCI.2011.06.003
Pipsa Saharinen, Lauri Eklund, Juho Miettinen, Riikka Wirkkala, Andrey Anisimov, Mark Winderlich, Astrid Nottebaum, Dietmar Vestweber, Urban Deutsch, Gou Young Koh, Bjorn R. Olsen, Kari Alitalo, Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts. Nature Cell Biology. ,vol. 10, pp. 527- 537 ,(2008) , 10.1038/NCB1715
Thomas A. Gaziano, Cardiovascular Disease in the Developing World and Its Cost-Effective Management Circulation. ,vol. 112, pp. 3547- 3553 ,(2005) , 10.1161/CIRCULATIONAHA.105.591792
Mark Cornell Manning, Danny K. Chou, Brian M. Murphy, Robert W. Payne, Derrick S. Katayama, Stability of Protein Pharmaceuticals: An Update Pharmaceutical Research. ,vol. 27, pp. 544- 575 ,(2010) , 10.1007/S11095-009-0045-6
Nikola Arsic, Lorena Zentilin, Serena Zacchigna, Daniela Santoro, Giorgio Stanta, Alessandro Salvi, Gianfranco Sinagra, Mauro Giacca, Induction of functional neovascularization by combined VEGF and angiopoietin-1 gene transfer using AAV vectors Molecular Therapy. ,vol. 7, pp. 450- 459 ,(2003) , 10.1016/S1525-0016(03)00034-0
Hua Su, Junya Takagawa, Yu Huang, Janice Arakawa-Hoyt, Jennifer Pons, William Grossman, Yuet Wai Kan, Additive effect of AAV-mediated angiopoietin-1 and VEGF expression on the therapy of infarcted heart International Journal of Cardiology. ,vol. 133, pp. 191- 197 ,(2009) , 10.1016/J.IJCARD.2007.12.034
Inbar Freeman, Smadar Cohen, The influence of the sequential delivery of angiogenic factors from affinity-binding alginate scaffolds on vascularization. Biomaterials. ,vol. 30, pp. 2122- 2131 ,(2009) , 10.1016/J.BIOMATERIALS.2008.12.057
Jangwook Lee, Cheau Yih Tan, Sang-Kyung Lee, Yong-Hee Kim, Kuen Yong Lee, Controlled delivery of heat shock protein using an injectable microsphere/hydrogel combination system for the treatment of myocardial infarction. Journal of Controlled Release. ,vol. 137, pp. 196- 202 ,(2009) , 10.1016/J.JCONREL.2009.04.008
Ruth R. Chen, Eduardo A. Silva, William W. Yuen, David J. Mooney, Spatio–temporal VEGF and PDGF Delivery Patterns Blood Vessel Formation and Maturation Pharmaceutical Research. ,vol. 24, pp. 258- 264 ,(2007) , 10.1007/S11095-006-9173-4