Identifying core features of adaptive metabolic mechanisms for chronic heat stress attenuation contributing to systems robustness

摘要: The contribution of metabolism to heat stress may play a significant role in defining robustness and recovery systems; either by providing the energy metabolites required for cellular homeostasis, or through generation protective osmolytes. However, mechanisms which attenuation could be adapted metabolic processes as stabilizing strategy against thermal are still largely unclear. We address this issue metabolomic transcriptomic profiles populations along cline where two seagrass species, Zostera marina noltii, were found close proximity. Significant changes captured these profile comparisons detected, with larger response magnitude observed northern stress. Sucrose, fructose, myo-inositol identified most responsive 29 analyzed organic metabolites. Many key enzymes Calvin cycle, glycolysis pentose phosphate pathways also showed differential expression. reported comparison suggests that adaptive involved dampen impacts stress, interactions between metabolome proteome should further investigated systems biology understand robust design features abiotic