Percutaneous left atrial appendage closure

作者: F. Nietlispach , S. Gloekler , A. Khattab , T. Pilgrim , M. Schmid

DOI: 10.1016/J.EURGER.2012.03.012

关键词: CardiologyPericardial effusionAtrial fibrillationLocal anesthesiaPercutaneousInternal medicineComplicationMedicineSurgeryLeft atrialClopidogrelStroke

摘要: Abstract Introduction Atrial fibrillation is a growing epidemic in the western world. Stroke as most dreaded complication effectively prevented by oral anticoagulation. Although effective preventing stroke, anticoagulants come at price of bleeding complications. Concerns about lead to high rate drug discontinuation and reason many patients are not put on all. Percutaneous left atrial appendage (LAA) closure an excellent option for who cannot or do want be anticoagulants, since origin more than 90% clots arising from atrium. Methods Using femoral venous access, plug placed appendage, thereby excluding this embryologic remnant circulation. The procedure can performed outpatient basis. We report our own experience 100 using Amplatzer cardiac plug. Results One hundred (72 ± 10 years) underwent LAA only local anesthesia without transesophageal guidance. Imaging sizing was contrast injections through 13 French TorqVue delivery sheath, followed device implantation. Clopidogrel prescribed 1 month acetylsalicylic acid 3–6 months. successful 98% often conjunction with other interventional procedures. Periprocedural 6% (2% pericardial effusion, 2% embolization, transient neurologic symptoms) no long-term sequelae. Conclusion attractive alternative anticoagulation suffering fibrillation.

参考文章(30)
Comprehensive one stop-shop percutaneous cardiac intervention Cardiovascular Medicine. ,vol. 13, pp. 9999- 9999 ,(2010) , 10.4414/CVM.2010.01497
Véronique L Roger, Alan S Go, Donald M Lloyd-Jones, Robert J Adams, Jarett D Berry, Todd M Brown, Mercedes R Carnethon, Shifan Dai, Giovanni De Simone, Earl S Ford, Caroline S Fox, Heather J Fullerton, Cathleen Gillespie, Kurt J Greenlund, Susan M Hailpern, John A Heit, P Michael Ho, Virginia J Howard, Brett M Kissela, Steven J Kittner, Daniel T Lackland, Judith H Lichtman, Lynda D Lisabeth, Diane M Makuc, Gregory M Marcus, Ariane Marelli, David B Matchar, Mary M McDermott, James B Meigs, Claudia S Moy, Dariush Mozaffarian, Michael E Mussolino, Graham Nichol, Nina P Paynter, Wayne D Rosamond, Paul D Sorlie, Randall S Stafford, Tanya N Turan, Melanie B Turner, Nathan D Wong, Judith Wylie-Rosett, Véronique L Roger, Melanie B Turner, None, Heart Disease and Stroke Statistics—2011 Update A Report From the American Heart Association Circulation. ,vol. 123, ,(2011) , 10.1161/CIR.0B013E3182009701
Bernhard Meier, Igor Palacios, Stephan Windecker, Martin Rotter, Qi-Ling Cao, David Keane, Carlos E. Ruiz, Ziyad M. Hijazi, Transcatheter left atrial appendage occlusion with Amplatzer devices to obviate anticoagulation in patients with atrial fibrillation. Catheterization and Cardiovascular Interventions. ,vol. 60, pp. 417- 422 ,(2003) , 10.1002/CCD.10660
Birke Schneider, Claudia Stöllberger, Hans H. Sievers, Surgical closure of the left atrial appendage - a beneficial procedure? The Cardiology. ,vol. 104, pp. 127- 132 ,(2005) , 10.1159/000087632
Robert G. Hart, Lesly A. Pearce, Maria I. Aguilar, Meta-analysis: Antithrombotic Therapy to Prevent Stroke in Patients Who Have Nonvalvular Atrial Fibrillation Annals of Internal Medicine. ,vol. 146, pp. 857- 867 ,(2007) , 10.7326/0003-4819-146-12-200706190-00007
Jana G. Hashash, Wael Shamseddeen, Assaad Skoury, Nathalie Aoun, Kassem Barada, Gross lower gastrointestinal bleeding in patients on anticoagulant and/or antiplatelet therapy: Endoscopic findings, management, and clinical outcomes Journal of Clinical Gastroenterology. ,vol. 43, pp. 36- 42 ,(2009) , 10.1097/MCG.0B013E318151F9D7
Joseph L. Blackshear, John A. Odell, Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation The Annals of Thoracic Surgery. ,vol. 61, pp. 755- 759 ,(1996) , 10.1016/0003-4975(95)00887-X