Amplatzer left atrial appendage occlusion: single center 10-year experience.

摘要: OBJECTIVES To report a 10-year single center experience with Amplatzer devices for left atrial appendage (LAA) occlusion. BACKGROUND Intermediate-term outcome data following LAA occlusion are scarce. METHODS Short- and intermediate-term outcomes of patients who underwent were assessed. All procedures performed under local aesthesia without transesophageal echocardiography. Patients discharged on acetylsalicylic acid clopidogrel 1-6 months. RESULTS LAA was attempted in 152 (105 males, age 72 ± 10 years, CHA2 DS2 -Vasc-score 3.4 1.7, HAS-BLED-score 2.4 1.2). Nondedicated used 32 (21%, ND group) dedicated Cardiac Plugs 120 (79%, ACP group). A patent foramen ovale or septal defect access closed at the end 40 patients. The short-term safety endpoints (procedural complications, bleeds) occurred 15 (9.8%) efficacy (death, stroke, systemic embolization) 0 Device embolization more frequently as compared to group (5 12% vs. 2 2%). Mean follow up study population months (range 1-120). Late deaths cardiovascular, 7 noncardiac, 3 unexplained). Neurologic events 2, peripheral embolism 1, major bleeding 4 composite endpoint 7% patients. CONCLUSION LAA closure may be good alternative oral anticoagulation. This hypothesis needs tested randomized clinical trial ensure that all potential biases this observational accounted for.