Human seroprevalence indicating hantavirus infections in tropical rainforests of Côte d’Ivoire and Democratic Republic of Congo

摘要: Hantaviruses are members of the Bunyaviridae family carried by small mammals and causing human hemorrhagic fevers worldwide. In Western Africa, where a variety fever viruses occurs, indigenous hantaviruses have been molecularly found in animal reservoirs such as rodents, shrews, bats since 2006. To investigate contact to these hosts assess public health relevance for humans living tropical rainforest regions Central we performed cross-sectional seroprevalence study region Tai National Park Cote d´Ivoire Bandundu near Salonga Democratic Republic Congo. Serum samples were initially screened with enzyme-linked immunosorbent assays using nucleoproteins several diagnostic antigens. Positive results confirmed blotting immunofluorescence testing. Seroprevalence rates 3.9% (27/687) 2.4% (7/295), respectively, investigated d´Ivoire, this value was significantly higher than previously reported from neighboring country Guinea well South Africa. Our indicates an exposure West African areas. order pinpoint possible existence frequency clinical disease caused world, systematic investigations patients renal or respiratory symptoms required.