Personalized Oncology in Interventional Radiology

作者: Nadine Abi-Jaoudeh , Austin G. Duffy , Tim F. Greten , Elise C. Kohn , Timothy W.I. Clark

DOI: 10.1016/J.JVIR.2013.04.019

关键词: Medical physicsGenetic testingCancer researchMedicineMolecular ProfileTumor angiogenesisPersonalized medicineInterventional radiologyMolecular pathologyVEGF receptorsPersonalized oncology

摘要: As personalized medicine becomes more applicable to oncologic practice, image-guided biopsies will be integral for enabling predictive and pharmacodynamic molecular pathology. Interventional radiology has a key role in defining patient-specific management. Advances diagnostic techniques, genomics, proteomics enable window into subcellular mechanisms driving hyperproliferation, metastatic capabilities, tumor angiogenesis. A new era of evolved whereby clinical decisions are adjusted according patient’s profile. Several mutations markers already have been introduced standard practice. broader understanding oncology help interventionalists play greater therapy selection discovery.

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