Impact of the Early-Life Environment on the Epigenome and Behavioral Development
作者： Benoit Labonté , Gustavo Turecki , None
DOI: 10.1007/978-1-4614-8078-5_8
关键词: Suicidal behavior 、 Early life 、 Psychopathology 、 Developmental psychology 、 Epigenetics 、 H3k9 acetylation 、 Biology 、 Epigenome 、 Vulnerability 、 Regulation of gene expression
摘要: The environment in which we live, and especially the early-life environment, regulates our behavioral development. Adversity during early life is strongly associated with problems regulation psychopathology adulthood. Until recently, mechanisms responsible for changes induced by adversity were not clear. However, recent evidence suggests that induces through epigenetic controlling expression of genes involved behavior. Thus, epigenome mediates effects environmental variability on behavioral, physiological, pathological responses increasing vulnerability toward suicidal behaviors. Numerous findings animals humans support this view. This chapter reviews suggesting are impact gene brain risk
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