Genetic polymorphism, the immune response and chronic pancreatitis

作者: Adrian C. Bateman , W. Martin Howell

DOI: 10.1007/978-1-85233-904-3_25

关键词: Autoimmune pancreatitisPancreatitisDiabetes mellitusHereditary pancreatitisGastroenterologyCoeliac diseaseAbdominal painGenetic predispositionInternal medicineMalabsorptionMedicine

摘要: Chronic pancreatitis is characterised clinically by severe abdominal pain together with malabsorption and, in advanced disease, diabetes mellitus. The triggering event cannot be determined every case. However, chronic excess alcohol consumption the most common aetiological factor other cases occurring due to pancreatic duct occlusion, an inherited genetic predisposition (hereditary pancreatitis) or autoimmune pancreatitis.

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