A gel-precipitin test for the diagnosis of varicella.

作者: Miriam Granat , Philip A. Brunell , Bernard H. Cohen

DOI:

关键词: SmallpoxAntiserumVacciniaAntigenChickenpoxMedicineImmunologyImmunodiffusionDifferential diagnosisPrecipitinVirology

摘要: Varicella may be difficult to distinguish clinically from smallpox. Because of this difficulty, much anxiety has occurred when cases chickenpox are misdiagnosed as smallpox in areas where is not endemic. Surveillance also been complicated eradication programmes progress. A gel-diffusion test developed that can detect varicella-zoster (V-Z) antigen vesicular fluid. This simple test, which performed the field, identified V-Z fluid all 14 varicella or zoster were tested. No reactions observed with vaccinia precipitin antigen. The production tissue culture provided a positive control yielded lines identity vesicle material was used screen human sera for suitable antisera test.

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