Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers

作者: Mi Ran Kang , Min Sung Kim , Ji Eun Oh , Yoo Ri Kim , Sang Yong Song

DOI: 10.1002/IJC.24379

关键词: PathogenesisCancerIDH1BiologyProstateMutationPathologyUrinary bladderMissense mutationGene

摘要: … For example, recurrent mutations of EGFR in lung cancers, BCR/ABL translocations in … R132C is the second one.1, 2 In agreement with these, the IDH1 mutations detected in our …

参考文章(16)
Jim R Woodburn, Susan E Ashton, Simon P Guy, Keith H Gibson, Brenda J Curry, Andrew J Barker, Alan E Wakeling, ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy. Cancer Research. ,vol. 62, pp. 5749- 5754 ,(2002)
Hong Sug Kim, Jong Woo Lee, Young Hwa Soung, Won Sang Park, Su Young Kim, Jong Heun Lee, Jik Young Park, Youg Gu Cho, Chang Jae Kim, Seong Whan Jeong, Suk Woo Nam, Sang Ho Kim, Jung Young Lee, Nam Jin Yoo, Sug Hyung Lee, Inactivating Mutations of Caspase-8 Gene in Colorectal Carcinomas Gastroenterology. ,vol. 125, pp. 708- 715 ,(2003) , 10.1016/S0016-5085(03)01059-X
Xiang Xu, Jingyue Zhao, Zhen Xu, Baozhen Peng, Qiuhua Huang, Eddy Arnold, Jianping Ding, Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity Journal of Biological Chemistry. ,vol. 279, pp. 33946- 33957 ,(2004) , 10.1074/JBC.M404298200
Brian V. Geisbrecht, Stephen J. Gould, The HumanPICDGene Encodes a Cytoplasmic and Peroxisomal NADP+-dependent Isocitrate Dehydrogenase Journal of Biological Chemistry. ,vol. 274, pp. 30527- 30533 ,(1999) , 10.1074/JBC.274.43.30527
D. W. Parsons, S. Jones, X. Zhang, J. C.-H. Lin, R. J. Leary, P. Angenendt, P. Mankoo, H. Carter, I-M. Siu, G. L. Gallia, A. Olivi, R. McLendon, B. A. Rasheed, S. Keir, T. Nikolskaya, Y. Nikolsky, D. A. Busam, H. Tekleab, L. A. Diaz, J. Hartigan, D. R. Smith, R. L. Strausberg, S. K. N. Marie, S. M. O. Shinjo, H. Yan, G. J. Riggins, D. D. Bigner, R. Karchin, N. Papadopoulos, G. Parmigiani, B. Vogelstein, V. E. Velculescu, K. W. Kinzler, An Integrated Genomic Analysis of Human Glioblastoma Multiforme Science. ,vol. 321, pp. 1807- 1812 ,(2008) , 10.1126/SCIENCE.1164382
Thomas J. Lynch, Daphne W. Bell, Raffaella Sordella, Sarada Gurubhagavatula, Ross A. Okimoto, Brian W. Brannigan, Patricia L. Harris, Sara M. Haserlat, Jeffrey G. Supko, Frank G. Haluska, David N. Louis, David C. Christiani, Jeff Settleman, Daniel A. Haber, Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib The New England Journal of Medicine. ,vol. 350, pp. 2129- 2139 ,(2004) , 10.1056/NEJMOA040938
Chloé James, Valérie Ugo, Jean-Pierre Le Couédic, Judith Staerk, François Delhommeau, Catherine Lacout, Loïc Garçon, Hana Raslova, Roland Berger, Annelise Bennaceur-Griscelli, Jean Luc Villeval, Stefan N. Constantinescu, Nicole Casadevall, William Vainchenker, A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera Nature. ,vol. 434, pp. 1144- 1148 ,(2005) , 10.1038/NATURE03546
A W Braithwaite, C L Prives, p53: more research and more questions Cell Death & Differentiation. ,vol. 13, pp. 877- 880 ,(2006) , 10.1038/SJ.CDD.4401938
J W Lee, Y G Kim, Y H Soung, K J Han,, S Y Kim, H S Rhim, W S Min, S W Nam, W S Park, J Y Lee, N J Yoo, S H Lee, The JAK2 V617F mutation in de novo acute myelogenous leukemias Oncogene. ,vol. 25, pp. 1434- 1436 ,(2006) , 10.1038/SJ.ONC.1209163
Marcos Malumbres, Mariano Barbacid, RAS oncogenes: the first 30 years Nature Reviews Cancer. ,vol. 3, pp. 459- 465 ,(2003) , 10.1038/NRC1097