The observation and analysis of efficacy of duodenum-preserving pancreatic head resection for patients with chronic pancreatitis

摘要: Objective: To investigate and analyze the efficacy of duodenum-preserving pancreatic head resection (DPPHR) for treatment chronic pancreatitis (CP). Methods: A retrospective analysis was performed regarding a total 21 patients with CP combined intractable abdominal pain, jaundice, or duct stones who were admitted into Hepatobiliary Pancreatic Surgery Department Henan Province People's Hospital from February 2010 to March 2016. All underwent DPPHR, which included 15 males 6 females, aged 31-48 years, mean (39.5 ± 6.7) years. Patients’ 6-month postoperative fasting plasma glucose (FPB), oral tolerance test (2 h-OGTr), weight, pain (VAS visual method), diarrhea symptoms, quality life assessment (GLQI Scale) measured. Results: There no operative death in this group patients. The major complication postoperational leakage, five cases incidence 23.8% (5/21). Abdominal relieved 18 significantly reduce three occasional episodes upper pain. Pain scores decreased (7.8 3.6 58.1 5.6, P 0.05). 2 h-OGTr changes not statistically significant either ((8.0 0.6) mmol/L (7.9 mmol/L, P> No new diabetes case occurred during follow-up. body weight increased average increase (4.8 0.7) kg ((58.8 1.8) (53.9 2.0) kg, P<0.05)). In addition, also improved (78.1 7.3 61.0 6.2, P<0.05). Conclusion: DPPHR can relieve without compromising functions. It help improve CP.