[Screening and therapy of anal intraepithelial neoplasia (AIN) and anal carcinoma in patients with HIV-infection].

摘要: Anal intraepithelial neoplasia (AIN) is a potential precursor of invasive anal carcinoma. Introduction highly active antiretroviral therapy (HAART) in the treatment HIV infection substantially reduced incidence some diseases associated with opportunistic viral infections. However, AIN reported to increase and HAART seems have only little impact on regression or progression AIN. Paradoxically, improvement survival era results an increased risk cancer. The carcinoma amongst homosexual men higher compared normal population (35/100.000). This similar cervical cancer before screening for CIN cytology. Recent data suggest that even among HIV-infected individuals. Both entities share biologic similarities, including association human papillomavirus (HPV). Screening cytology early has resulted significant decline Like cancer, may be preventable through identification its precursors. Future efforts should focus protocol, training clinicians diagnosis carcinoma, novel approaches these lesions. protocol could help reduce HIV-infection as well save limited resources health care system.