1 – Vitamin E and Lung Cancer Prevention

摘要: Publisher Summary In earlier studies on serum or dietary vitamin E status and lung cancer occurrence, a significantly reduced risk of at higher levels was found only among nonsmokers. In both nonsmokers smokers, the inverse association between simultaneously high α-tocopherol, β-carotene, retinol, selenium, stronger than for single nutrients. This chapter argues that selenium α-tocopherol apparently compensate each other. Furthermore, it present an antioxidant index combining is mainly due to selenium. Evidence protective effect against not conclusive. may be partly methodological issues involved in different study designs, accordingly, cannot excluded E, some circumstances, provides protection disease. Studies simultaneous effects other micronutrients, various categories exposure tobacco smoke, are accordance with this hypothesis. To obtain more reliable information possible risk, circumstances effect, meta-analyses previously published observational new large studies, special emphasis interactions issues, should carried out. When becomes available, intervention trials could