Associations of Spatial Disparities of Alzheimer's Disease Mortality Rates with Soil Selenium and Sulfur Concentrations and Four Common Risk Factors in the United States.
作者： Hongbing Sun
DOI: 10.3233/JAD-170059
关键词: Mortality rate 、 Spatial disparity 、 Biology 、 Obesity 、 Inverse correlation 、 Disease mortality 、 Selenium 、 Animal science 、 Sulfur 、 Rate ratio 、 Environmental health
摘要: BACKGROUND Associations between environmental factors and spatial disparity of mortality rates Alzheimer's disease (AD) in the US are not well understood. OBJECTIVE To find associations 41 trace elements, four common risk factors, AD the48 contiguous states. METHODS Isopleth maps 48 states associated were examined. Correlations state average concentrations soil wine consumption, percentage current smokers, obesity, diagnosed diabetes 1999 2014 analyzed. RESULTS Among selenium have most significant inverse correlations with rates. Rate ratio (RR) 6 lowest product sulfur is 53% higher than highest (RR = 1.53, CI95% 1.51-1.54). Soil tin correlation growth 2014, followed by concentrations. Percentages diabetes, smoking, consumption per capita also correlate significantly CONCLUSIONS High low Given that indicators their intakes from food, water, air people a region, long-term exposure to high might be beneficial rate reduction region.
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