Bone Morphogenetic Protein (BMP) signaling in development and human diseases.

作者: Richard N. Wang , Jordan Green , Zhongliang Wang , Youlin Deng , Min Qiao

DOI: 10.1016/J.GENDIS.2014.07.005

关键词: Bone morphogenetic proteinCell signalingEmbryonic stem cellBMPR2Cell biologyBioinformaticsBMP signaling pathwayBiologyTransforming growth factorSignal transductionTissue homeostasis

摘要: Bone Morphogenetic Proteins (BMPs) are a group of signaling molecules that belongs to the Transforming Growth Factor-β (TGF-β) superfamily of proteins. Initially discovered for their …

参考文章(279)
Jochen Graw, Chapter Ten – Eye Development Current Topics in Developmental Biology. ,vol. 90, pp. 343- 386 ,(2010) , 10.1016/S0070-2153(10)90010-0
Jiang-Yue Zhao, Jin-Song Zhang, Qi Zhao, Zhi-Yu Zhang, Xiang-Chuan Lu, Di Wu, Mutually inductive interactions between the lens and retina require ALK3 functions during mouse embryonic development. International Journal of Ophthalmology. ,vol. 5, pp. 119- 124 ,(2012) , 10.3980/J.ISSN.2222-3959.2012.02.01
Aaron Daluiski, Thomas Engstrand, Matthew E Bahamonde, Laura W Gamer, Eric Agius, Sharon L Stevenson, Karen Cox, Vicki Rosen, Karen M Lyons, None, Bone morphogenetic protein-3 is a negative regulator of bone density. Nature Genetics. ,vol. 27, pp. 84- 88 ,(2001) , 10.1038/83810
James R. Howe, Jennifer L. Bair, Mohamed G. Sayed, Mary E. Anderson, Frank A. Mitros, Gloria M. Petersen, Victor E. Velculescu, Giovanni Traverso, Bert Vogelstein, Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis Nature Genetics. ,vol. 28, pp. 184- 187 ,(2001) , 10.1038/88919
Alexandra C. McPherron, Ann M. Lawler, Se-Jin Lee, Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11 Nature Genetics. ,vol. 22, pp. 260- 264 ,(1999) , 10.1038/10320
Meredith L Hanel, Carmel Hensey, Eye and neural defects associated with loss of GDF6 BMC Developmental Biology. ,vol. 6, pp. 43- 43 ,(2006) , 10.1186/1471-213X-6-43
Ronggui Li, Alexander Rosendahl, Greger Brodin, Alec M. Cheng, Aive Ahgren, Christina Sundquist, Sarang Kulkarni, Tony Pawson, Carl-Henrik Heldin, Rainer L. Heuchel, Deletion of Exon I of SMAD7 in Mice Results in Altered B Cell Responses Journal of Immunology. ,vol. 176, pp. 6777- 6784 ,(2006) , 10.4049/JIMMUNOL.176.11.6777
Carl-Henrik Heldin, Kohei Miyazono, Peter ten Dijke, TGF-beta signalling from cell membrane to nucleus through SMAD proteins Nature. ,vol. 390, pp. 465- 471 ,(1997) , 10.1038/37284
J. M. Fletcher, S. J. Lalor, C. M. Sweeney, N. Tubridy, K. H. G. Mills, T cells in multiple sclerosis and experimental autoimmune encephalomyelitis Clinical and Experimental Immunology. ,vol. 162, pp. 1- 11 ,(2010) , 10.1111/J.1365-2249.2010.04143.X
Masanobu Oshima, Akihiro Matsunaga, Nobuya Sasaki, Makoto M. Taketo, Kazuaki Takaku, Hiroyuki Miyoshi, Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice. Cancer Research. ,vol. 59, pp. 6113- 6117 ,(1999)