Subclinical hyperthyroidism: clinical features and treatment options

摘要: Subclinical hyperthyroidism appears to be a common disorder. It may caused by exogenous or endogenous factors: excessive TSH suppressive therapy with L-thyroxine (L-T4) for benign thyroid nodular disease, differentiated cancer, hormone over-replacement in patients hypothyroidism are the most frequent causes. Consistent evidence indicates that 'subclinical' reduces quality of life, affecting both psycho and somatic components well-being, produces relevant signs symptoms action, often mimicking adrenergic overactivity. exerts many significant effects on cardiovascular system; it is usually associated higher heart rate risk supraventricular arrhythmias, an increased left ventricular mass, accompanied impaired diastolic function sometimes reduced systolic performance effort decreased exercise tolerance. well known these abnormalities precede onset more severe thus potentially contributing morbidity mortality observed patients. In addition, becoming increasingly apparent subclinical accelerate development osteoporosis hence bone vulnerability trauma, particularly postmenopausal women pre-existing predisposition. its related clinical manifestations reversible prevented timely treatment.