Skin Cancer in the Crosshairs: Highlights from the Biennial Scientific Retreat of International Transplant Skin Cancer Collaborative and Skin Care in Organ Transplant Recipients Europe.

作者: Sudipta Sinnya , Fiona O. Zwald , Oscar R. Colegio

DOI: 10.1097/TXD.0000000000000535

关键词: Intensive care medicineMelanomaSurgeryOrgan transplantationMerkel cell carcinomaImmunosuppressionLymphoproliferative disordersMedicineSkin cancerBasal cell carcinomaSolid organ

摘要: The International Transplant Skin Cancer Collaborative (ITSCC) is an organization comprising of physicians; transplant surgeons and basic science research scientists dedicated in providing optimal care ongoing advancements solid organ recipients to improve patient outcome quality life. As medical advances occur, it anticipated that the sheer number transplantations occurring worldwide will continue increase. long-term medication associated immunosuppression improves graft survival, but as a consequence, these individuals become increasingly susceptible various cutaneous malignancies, lymphoproliferative disorders infections. Squamous cell carcinoma most frequently encountered skin cancer increases 65- 250-fold [Jensen et al., kidney heart different immunosuppressive therapy regimens. J Am Acad Dermatol. 1999;40:177-186; Lindelof Incidence 5356 patients following transplantation. Br 2000; 143:513-519]. However, rates basal carcinoma, Merkel melanoma also increase leading significant morbidity well mortality [Berg Otley. recipients: epidemiology, pathogenesis, management. 2002; 47:1-20]. In October 2014, its equivalent European counterpart, Care Organ Recipients Europe held 10th biennial meeting Essex, MA discuss clinical conundrums evolving pertinent field. This report provides synthesis all data presented at 4-day meeting.

参考文章(22)
I. Fried, L. Cerroni, Merkel-Zell-Karzinom Pathologe. ,vol. 35, pp. 467- 475 ,(2014) , 10.1007/S00292-014-1935-X
J. N. Bouwes Bavinck, C. A. Harwood, R. E. Genders, H. C. Wisgerhof, E. I. Plasmeijer, L. Mitchell, E. B. Olasz, D. D. Mosel, M. S. Pokorney, A. L. Serra, L. Feldmeyer, K. Baumann Conzett, S. Piaserico, A. Belloni Fortina, K. Jahn, A. Geusau, M. J. P. Gerritsen, D. Seçkin, A. T. Güleç, P. Cetkovská, J. Ricar, B. Imko-Walczuk, C. M. Proby, G. F. L. Hofbauer, Pain identifies squamous cell carcinoma in organ transplant recipients: the SCOPE-ITSCC PAIN study American Journal of Transplantation. ,vol. 14, pp. 668- 676 ,(2014) , 10.1111/AJT.12587
Werner Kempf, Kirsten D. Mertz, Jean Kanitakis, Günther F.L. Hofbauer, Critical skin cancer in organ transplant recipients--a dermatopathological view. Current problems in dermatology. ,vol. 43, pp. 18- 35 ,(2012) , 10.1159/000335144
Yaxia Zhang, Phillip Ruiz, Solid Organ Transplant-Associated Acute Graft-Versus-Host Disease Archives of Pathology & Laboratory Medicine. ,vol. 134, pp. 1220- 1224 ,(2010) , 10.1043/2008-0679-RS.1
Tejaswi Mudigonda, Daniel J. Pearce, Brad A. Yentzer, Phillip Williford, Steven R. Feldman, The economic impact of non-melanoma skin cancer: a review. Journal of The National Comprehensive Cancer Network. ,vol. 8, pp. 888- 896 ,(2010) , 10.6004/JNCCN.2010.0066
Anna L. Taylor, Paul Gibbs, J. Andrew Bradley, Acute Graft Versus Host Disease Following Liver Transplantation: The Enemy Within American Journal of Transplantation. ,vol. 4, pp. 466- 474 ,(2004) , 10.1111/J.1600-6143.2004.00406.X
J.F Buell, J Trofe, M.J Hanaway, T.M Beebe, T.G Gross, R.R Alloway, M.R First, E.S Woodle, Immunosuppression and Merkel cell cancer. International Congress on Immunosuppression. ,vol. 34, pp. 1780- 1781 ,(2002) , 10.1016/S0041-1345(02)03065-8
Rubeta Nh Matin, D Mesher, CM Proby, JM McGregor, Jan Nico Bouwes Bavinck, Véronique Del Marmol, Sylvie Euvrard, C Ferrandiz, Alexandra Geusau, Monika Hackethal, WenLyn Ho, GFL Hofbauer, Beata Imko‐Walczuk, Jean Kanitakis, A Lally, JT Lear, Céleste Lebbe, GM Murphy, Stefano Piaserico, Deniz Seckin, Eggert Stockfleth, Claas Ulrich, FT Wojnarowska, HY Lin, Charles Balch, Catherine Anne Harwood, Skin Care in Organ Transplant Patients, Europe (SCOPE) group, Melanoma in organ transplant recipients: clinicopathological features and outcome in 100 cases. American Journal of Transplantation. ,vol. 8, pp. 1891- 1900 ,(2008) , 10.1111/J.1600-6143.2008.02326.X
Daniel Berg, Clark C. Otley, Skin cancer in organ transplant recipients: Epidemiology, pathogenesis, and management. Journal of The American Academy of Dermatology. ,vol. 47, pp. 1- 20 ,(2002) , 10.1067/MJD.2002.125579