The effects of acute altitude exposure in swiss highlanders and lowlanders

摘要: The functional characteristics at rest in responding to stepwise acute exposure simulated altitude (6000 m) were compared 10 acclimatized mountaineers (highlanders), residents of Zermatt (1616 working an up about 4000 m, and 11 nonacclimatized control subjects (lowlanders) living Zurich (450 m). In comparison with the lowlanders, highlanders showed significantly greater hyperventilation, lower heart rate systolic blood pressure, smaller haemoconcentration, urodilatin secretion natriuresis, a preserved neuropsychological ability (attentiveness) vasomotor tone (diastolic pressure); critical which hypoxic short-term adaptation became insufficient was 6000 m. however, manifested reduced tolerance hypoxia, i.e. adjustment subjective objective distress coinciding first signs hypoxia central nervous system, already apparent above It concluded that differences between lowlanders gradual indicated factors contributing acclimatization.