Effects of tracheostomy breathing on brain and body temperatures in hyperthermic sheep.

作者: H P Laburn , D Mitchell , G Mitchell , K Saffy

DOI: 10.1113/JPHYSIOL.1988.SP017383

关键词: Temperature differenceAnesthesiaMedicineTreadmillHyperthermiaRectal temperatureBreathingRespiratory tractBrain coolingHypothalamic temperature

摘要: 1. We measured rectal and hypothalamic temperature in sheep breathing nasally via a tracheostomy, during hyperthermia resulting from exposure to hot environment, exercise fever. 2. In normothermic hyperthermic was up 1.0 degree C lower than when the breathed nasally. Tracheostomy abolished rectal-hypothalamic difference. 3. tracheostomy exposed dry-bulb of 45-50 degrees for 2 h, exceeded by about 0.4 C, significantly higher that same environment. 4. During on treadmill post-exercise period, difference between while through rose levels compared those evident activity 5. After an I.V. injection micrograms/kg lipopolysaccharide (LPS), again but less 6. Our results indicate selective brain cooling depends upper respiratory tract normo- states sheep.

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