Facing the Future of Brain Tumor Clinical Research

作者: Mark R. Gilbert , Terri S. Armstrong , Whitney B. Pope , Martin J. van den Bent , Patrick Y. Wen

DOI: 10.1158/1078-0432.CCR-14-0835

关键词: Clinical trialBrain tumorPediatric Brain TumorClinical researchPatient treatmentClinical study designCancerMedical physicsPathologyMedicinePediatric brain

摘要: This edition of CCR Focus provides critical reviews several important areas in the field, including application findings from genomic investigations brain tumors to improve diagnosis, clinical trial design, and ultimately optimizing individual patient treatment. Another article is a review provided by experts field that discusses recent trials using angiogenesis inhibitors, possible explanations for results, how move forward. There concise discussion immunotherapy key investigators this reflecting potential opportunities as well disease-specific challenges. Finally, leading pediatric tumor provide an overview insights about seminal discoveries two tumors, supporting paradigm laboratory lead more precise prognosis, better Herein, advances challenges area translational research set stage contributions follow. See all articles section, “Discoveries, Challenges, Progress Primary Brain Tumors.” Clin Cancer Res; 20(22); 5591–600. ©2014 AACR .

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