Effects of different doses of oral ketamine for premedication of children.

作者: S. Turhanoğlu , A. Kararmaz , M. A. Özyilmaz , S. Kaya , D. Tok

DOI: 10.1017/S0265021503000103

关键词: KetamineSedativeAnesthesiaElective surgeryPlacebo-controlled studyPremedicationSurgeryGeneral anaesthesiaSedationOral administrationMedicine

摘要: Summary Background and objective: A need exists for a safe effective oral preanaesthetic medication use in children undergoing elective surgery. The study sought to define the dose of ketamine that would facilitate induction anaesthesia without causing significant side-effects. Methods: We studied 80 surgery under general who received 4, 6 or 8 mg kg −1 prospective, randomized, double-blind placebo controlled study. compared reaction separation from parents, transport operating room, response intravenous cannula insertion application an anaesthetic facemask, recovery anaesthesia. Results: In group receiving , were significantly calmer than those other groups, was more comfortable. Recovery longer with but no differences between groups observed after 2 h room. Conclusions: It is concluded premedication inpatient

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