Next-Generation Sequencing Technologies and Formalin-Fixed Paraffin-Embedded Tissue: Application to Clinical Cancer Research

作者: Nadine Norton

DOI: 10.1007/978-3-319-15811-2_9

关键词: MedicineParaffin embeddingCancer treatmentFormalin fixed paraffin embeddedCancerTissue bankCancer genome sequencingStandard treatmentSingle cell sequencingCancer research

摘要: Billions of tissue samples are now archived by formalin fixation paraffin embedding (FFPE) in banks and hospitals around the world. For those biomarkers measured immunohistochemistry used today as a standard care cancer treatment, this method preservation works well. However, heterogeneous nature disease means that many patients do not respond or relapse under treatment.

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