X-ray diffraction studies of concentrated gels of ribosomes from E. coli

作者: Robert Langridge , Kenneth C. Holmes

DOI: 10.1016/S0022-2836(62)80089-8

关键词: Reflection (mathematics)RibosomeDiffractionCrystallographyLinear polymerChemistryX-ray crystallography

摘要: X-ray diffraction patterns showing 9 maxima at spacings greater than 10 A have been obtained from concentrated gels of E. coli 50 s ribosomes. The observed can be fitted to integral orders 212 basic repeat, with the exception a reflection 45·5 A. It is suggested that both and 70 particles form linear polymer in gel repeat spacing believed arise some internal structure ribosome.

参考文章(11)
A. Tissières, J.D. Watson, D. Schlessinger, B.R. Hollingworth, Ribonucleoprotein particles from Escherichia coli Journal of Molecular Biology. ,vol. 1, pp. 221- 233 ,(1959) , 10.1016/S0022-2836(59)80029-2
W. Fuller, Two-stranded helical configurations for ribonucleic acid Journal of Molecular Biology. ,vol. 3, pp. 175- 184 ,(1961) , 10.1016/S0022-2836(61)80044-2
G. Zubay, M.H.F. Wilkins, X-ray diffraction studies of the structure of ribosomes from Escherichia coli Journal of Molecular Biology. ,vol. 2, pp. 105- IN4 ,(1960) , 10.1016/S0022-2836(60)80032-0
A. TISSIÈRES, J. D. WATSON, Ribonucleoprotein particles from Escherichia coli. Nature. ,vol. 182, pp. 778- 780 ,(1958) , 10.1038/182778B0
C.E. Hall, H.S. Slayter, Electron microscopy of ribonucleoprotein particles from E. Coli Journal of Molecular Biology. ,vol. 1, pp. 329- IN1 ,(1959) , 10.1016/S0022-2836(59)80014-0
H.E. Huxley, G. Zubay, Electron microscope observations on the structure of microsomal particles from Escherichia coli Journal of Molecular Biology. ,vol. 2, pp. 10- IN8 ,(1960) , 10.1016/S0022-2836(60)80003-4
William E. Dibble, Howard M. Dintzis, The size and hydration of rabbit-reticulocyte ribosomes Biochimica et Biophysica Acta. ,vol. 37, pp. 152- 153 ,(1960) , 10.1016/0006-3002(60)90093-7
G. E. Palade, P. Siekevitz, PANCREATIC MICROSOMES: AN INTEGRATED MORPHOLOGICAL AND BIOCHEMICAL STUDY Journal of Cell Biology. ,vol. 2, pp. 671- 690 ,(1956) , 10.1083/JCB.2.6.671
R. C. Jones, X-ray diffraction by randomly oriented line gratings Acta Crystallographica. ,vol. 2, pp. 252- 257 ,(1949) , 10.1107/S0365110X49000643
A. Klug, K.C. Holmes, J.T. Finch, X-ray diffraction studies on ribosomes from various sources Journal of Molecular Biology. ,vol. 3, pp. 87- 100 ,(1961) , 10.1016/S0022-2836(61)80010-7