Establishing the Architecture of Plant Gene Regulatory Networks.

摘要: Abstract Gene regulatory grids (GRGs) encompass the space of all possible transcription factor (TF)–target gene interactions that regulate expression, with networks (GRNs) representing a temporal and spatial manifestation portion GRG, essential for specification expression. Thus, understanding GRG architecture provides valuable tool to explain how genes are expressed in an organism, important aspect synthetic biology toward development “in silico” cell. Progress has been made some unicellular model systems (eg, yeast), but significant challenges remain more complex multicellular organisms such as plants. Key organization GRGs is therefore identifying TFs bind to, control. The application sensitive high-throughput methods investigate genome-wide TF–target providing wealth information can be linked agronomic traits. We describe here resources have developed plant GRNs. also provide regarding where obtain clones or other necessary metabolic engineering.