Associations between body mass index trajectories in childhood and cardiovascular risk factors in adulthood.

摘要: Abstract Background and aims Children with a growth trajectory of overweight have higher levels cardiovascular disease (CVD) risk factors than children normal-weight trajectory. However, less is known about how trajectories body mass index (BMI) across the rest BMI spectrum relate to CVD whether adult affects these associations. Our aim was examine associations between childhood factors. Methods We included 2466 individuals weights heights (ages 6–14) from Copenhagen School Health Records Register 20–81) City Heart Study. Associations identified by latent class modelling were examined using generalized linear regression analyses without adjustment for BMI. Normal-weight defined references Centers Disease Control Prevention. Results four within one overweight. Compared lowest level, several associated worse circumference, HDL glucose homeostasis in adulthood. The highest additionally total cholesterol triglycerides. When adjusting BMI, had lower waist blood pressure Conclusions Trajectories range are profile trajectory, modifiable after childhood.