Fixed-combination clindamycin 1%-benzoyl peroxide 5% hydrating gel: a flexible component of acne management

摘要: This article reviews various studies supporting the use of a fixed-combination monotherapy hydrating gel containing clindamycin 1% and benzoyl peroxide 5% (C/BPO), which is only available formulation with vehicle humectant an occlusive. The C/BPO provides flexible complementary efficacy and/or tolerability profile when used alone or topical retinoids, results in rapid response inflammatory noninflammatory acne. It also mitigates irritation associated disease flare retinoid use, reduces postinflammatory hyperpigmentation (PIH) seen women patients skin color These benefits are important because they have potential to improve patient adherence therapy clinical outcomes.