Synthesis of L-trehalose and observations on isomer and by-product formation.
作者： Alan H Haines
DOI: 10.1016/S0008-6215(03)00043-0
关键词: Trehalose 、 Reaction conditions 、 Biomolecule 、 Chemistry 、 Trimethylsilyl 、 Stereochemistry 、 Disaccharide 、 Dehydration 、 By-product
摘要: Abstract With a view to gaining evidence on the mechanism by which d -trehalose is able stabilise biomolecules towards dehydration (anhydrobiosis) and heat, l has been prepared in order allow comparative studies be made. Little change can induced ratio of α,α-, α,β-, β,β-1,1′-stereoisomers disaccharide formed from 2,3,4,6-tetra-O-benzyl- -glucose using different reaction procedures varying conditions. Benzyl 2,3,4,6-tetra-O-benzyl α- β- -glucopyranoside are by-products trimethylsilyl trifluoromethanesulphonate mediated formation 1,1′-linked disaccharides.
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