Identification and treatment of antidepressant tachyphylaxis.

作者: Steven D Targum

DOI:

关键词: MedicineDrugMedication NonadherenceMajor depressive disorderTreatment interventionAntidepressantTreatment responsePharmacologyDrug toleranceTachyphylaxisIntensive care medicine

摘要: Antidepressant tachyphylaxis describes a condition in which depressed patient loses previously effective antidepressant treatment response despite staying on the same drug and dosage for maintenance treatment. It has been suggested that is form of relapse related to evolving tolerance, but it also clear there are other possible reasons loss unrelated such as medication nonadherence. reported patients with "true" may be less responsive new interventions. Therefore, important identify these part comprehensive planning process.

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