The 3-Hole Minimally Invasive Esophagectomy: A Safe Procedure Following Neoadjuvant Chemotherapy and Radiation

摘要: Induction therapy followed by esophagectomy has become standard for treatment of intermediate-stage esophageal cancer in many centers. Herein we evaluate the feasibility and safety 3-hole minimally invasive (3HMIE) approach patients who received induction radiation chemotherapy. Between 2003 2012, records 119 consecutive with underwent 3HMIE were reviewed perioperative complications long-term outcomes. Comparison was made between procedures performed receiving neoadjuvant chemoradiation treated only surgery. Of them, 78 41 Tumor locations upper (2), middle (16), distal (64), gastroesophageal junction (37). In all, 76 at clinical stage IIA or above presentation. Increased requirement blood replacement group significant compared surgery-only group. Operative time, estimated loss, proximal margin lengths, length stay not significantly different cohorts. There a 30-day death (0.8%), this patient from No conduit necrosis need diversion recorded. Overall, 5-year survival 62% among 107 early-stage cancer. is feasible low mortality acceptable morbidity even locally advanced radiochemotherapy. Overall outcomes are similar to better than those reported published literature on after therapy.