Methods for using alkanoyloxymethyl esters

作者: Norbert L. Wiech , Hsuan-Yin Lan-Hargest

DOI:

关键词: CancerPropionateBiochemistryHistone deacetylaseButyrateChemistry

摘要: Methods of using propionoyloxymethyl propionate (“POMP”) and butyroyloxymethyl butyrate (“BOMB”) are disclosed. treating cancer these compounds The effective in the inhibition histone deacetylase.

参考文章(9)
Daniel L. Kensler, David D. Walgenbach, Gustave K. Kohn, Fungus and bacteria control with di-carboxylic acid esters ,(1974)
Daniel L. Kensler, David D. Walgenbach, Gustave K. Kohn, Oxymethylene di-carboxylic acid esters as anti-fungal agents and animal growth promoters ,(1975)
Ada Rephaeli, Abraham Nudelman, Matityahu Shaklai, Methods of using carboxylic acid esters to increase fetal-hemoglobin levels ,(1994)
Ada Rephaeli, Abraham Nudelman, Nitrogen-containing oxyalkylene esters and uses thereof ,(1998)
Bernard Loev, Ada Rephaeli, Edward Neiss, Abraham Nudelman, Metabolically stabilized oxyalkylene esters and uses thereof ,(1998)
Abraham Nudelman, Margaretta Ruse, Adina Aviram, Ester Rabizadeh, Matityahu Shaklai, Yael Zimrah, Ada Rephaeli, Novel anticancer prodrugs of butyric acid. 2. Journal of Medicinal Chemistry. ,vol. 35, pp. 687- 694 ,(1992) , 10.1021/JM00082A009
Matitiahu Shaklai, Abraham Nudelman, Ada Rephaeli, Biologically active carboxylic acid esters ,(1988)