Precancerous Changes in the Stomach

摘要: Summary Intestinal metaplasia is often associated with human gastric carcinoma. Intestinalization seems to be a typical example of abnormal differentiation and possibly precancerous state. For investigation intestinal metaplasia, method for visualizing disaccharidases using Tes-Tape was developed; this applied many specimens stomach surgically removed the treatment More than 130 were investigated. classified into types I II metaplasia. In type sucrase, maltase, trehalase, alkaline phosphatase, goblet cells, Paneth cells present; while sucrase maltase present but phosphatase trehalase absent. II, not cells. The histochemical technique newly devised. Some villi in area intestinalization stained by activity, although most stained. presence third suggested. Purified sucrases obtained from intestine one case showed blood group reactivity due oligosaccharide side chain. However, purified two cases negative reactivity. A close relation between distribution α-fetoprotein carcinoembryonic antigen carcinoma that surrounding discussed.